– Our Vision –
Our vision is that every patient should have access to the most up-to-date individualised treatments and innovative therapies. By strengthening shared decision-making through dynamic computer-interpretable guidelines (CIGs), innovative access to broad data sets and AI-driven technology and tools, we envision revolutionising oncology care in Europe.
What are
we aiming for?
Implementation of a vast federated and centralised network of European data providers to help answer the highest priority research questions in prostate, breast and lung cancer, especially where the existing evidence underpinning clinical practice guidelines is weak or lacking.
In parallel, the development and application in clinical settings of comprehensive dynamic computer-interpretable guidelines to better support shared decision making by clinicians and patients. The CIGs will be updated when research questions are answered or AI models provide refinements after robust clinical validation.
Which challenges
are addressed?
Challenges for patients
For patients, the increasing complexity of diagnostics and treatments available are difficult to comprehend. This poses a significant barrier to patients receiving optimal individualised treatment and care within a shared decision-making framework with their clinician.
Challenges for clinicians
For clinicians, the tremendous volume of rapidly changing information on new diagnostic tests, novel treatments, and guidelines poses a formidable challenge when deciding the optimal treatment for their patients.
Challenges for pharmaceutical companies & regulators
For pharmaceutical companies and regulators, understanding real-world treatment outcomes of novel compounds outside of well controlled randomised controlled trials (RCTs) has become a vital component of drug development, regulatory approval, access to market, and post-market assessment.
Challenges for healthcare payers
For healthcare payers, the scarcity of reliable and complete real-world evidence on the effectiveness and real-world safety of treatments complementary to RCTs data prevents real-time decision-making and effective management of resources.
Challenges for healthcare ecosystems
For healthcare ecosystems, experiencing a shift from organisation-focused to patient-focused healthcare has triggered the implementation of a new and technology-enabled healthcare ecosystem. The digital revolution challenges the status quo and requires new infrastructures in place to ensure innovative care models can be implemented into routine clinical practice.
Principles & Key Objectives
Availability to all relevant stakeholders
Establish a data catalogue by gathering and harmonising large-scale structured and unstructured real-world datasets from European EHR and other types of real-world data.
Trust and Acceptability to stakeholders such as physicians and patients
Develop a scalable and regularly updated guideline decision-support toolset as part of the platform for the three prioritised indications prostate, breast, and lung cancer.
Real added Value for all stakeholders
- Drive new knowledge generation through advanced analytics and AI-models
- Ensure the sustainability of OPTIMA’s platform by supporting business models based on commercial users
Sustainability in terms of operational capacity beyond the duration of the action
Develop and implement a secure, sustainable, valuable, and interoperable platform to host harmonization tools, federated learning tools and AI algorithms, and guideline-based decision support tools.
Availability to all relevant stakeholders
Establish a data catalogue by gathering and harmonising large-scale structured and unstructured real-world datasets from European EHR and other types of real-world data.
Trust and Acceptability to stakeholders such as physicians and patients
Develop a scalable and regularly updated guideline decision-support toolset as part of the platform for the three prioritised indications prostate, breast, and lung cancer.
Sustainability in terms of operational capacity beyond the duration of the action
Real added Value for all stakeholders
- Drive new knowledge generation through advanced analytics and AI-models
- Ensure the sustainability of OPTIMA’s platform by supporting business models based on commercial users
Work Packages
Dedicated groups to
reach our goals.
Work Packages
Dedicated groups to
reach our goals.
